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Symbol Name ID |
Gria2
glutamate receptor, ionotropic, AMPA2 (alpha 2) MGI:95809 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Mouse Phenotypes | nervous system phenotype |
seizures |
tonic-clonic seizures |
increased susceptibility to neuronal excitotoxicity |
abnormal neuron differentiation |
abnormal brain interneuron morphology |
abnormal ventromedial hypothalamic nucleus morphology |
abnormal amygdala morphology |
abnormal hippocampus CA3 region morphology |
hippocampal neuron degeneration |
loss of hippocampal neurons |
abnormal CNS glial cell morphology |
gliosis |
motor neuron degeneration |
abnormal spinal cord morphology |
abnormal spinal cord ventral horn morphology |
decreased spinal cord ventral horn cell number |
abnormal nervous system electrophysiology |
impaired synaptic plasticity |
abnormal excitatory postsynaptic currents |
abnormal excitatory postsynaptic potential |
abnormal glutamate-mediated receptor currents |
abnormal AMPA-mediated synaptic currents |
enhanced AMPA-mediated synaptic currents |
enhanced long-term potentiation |
absent long-term depression |
abnormal paired-pulse facilitation |
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| Availability | Mouse Genotype | |||||||||||||||||||||||||||
| Gria2tm1.1Phs/Gria2tm1.1Phs | * | |||||||||||||||||||||||||||
| Gria2tm1Phs/Gria2tm1Phs | * | |||||||||||||||||||||||||||
| Gria2tm1Rlh/Gria2tm1Rlh | ||||||||||||||||||||||||||||
| Gria2tm1Rod/Gria2tm1Rod | ||||||||||||||||||||||||||||
| Gria2tm2Rlh/Gria2tm2Rlh | ||||||||||||||||||||||||||||
| Gria2tm2Rsp/Gria2tm2Rsp | ||||||||||||||||||||||||||||
| Gria2tm3.1Rsp/Gria2tm3.1Rsp | ||||||||||||||||||||||||||||
| Gria2tm1Rod/Gria2+ | ||||||||||||||||||||||||||||
| Gria2tm1Rsp/Gria2+ | ||||||||||||||||||||||||||||
| Gria2tm2.1Rsp/Gria2+ | ||||||||||||||||||||||||||||
| Gria2tm2Rsp/Gria2+ | ||||||||||||||||||||||||||||
| Gria2tm2Rsp/Gria2+ Tg(Gria2*586N)238.2Rsp/0 |
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| Tg(Gria2*586N)238.2Rsp/0 | ||||||||||||||||||||||||||||
| Gria2tm1.1Bvis/Gria2tm1.1Bvis Tg(Camk2a-cre)T29-1Stl/0 (conditional) |
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| Gria2tm3Rsp/Gria2tm3Rsp Tg(Camk2a-cre)1Gsc/0 (conditional) |
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| Gria2tm3Rsp/Gria2tm3Rsp Tg(Gnrh1-cre)1Rsp/0 (conditional) |
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| Gria2tm3Rsp/Gria2tm3Rsp Tg(Slc6a3-icre)9075Gsc/0 (conditional) |
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| Gria2tm2Rsp/Gria2+ Tg(Camk2a-cre)1Gsc/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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